NCT00618007已完成2 期
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study To Evaluate The Efficacy And Safety Of 12-Week Administration Of PF-00734200 To Subjects With Type 2 Diabetes Mellitus And Insufficient Glycemic Control On Metformin Treatment
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- Pfizer
- 入组人数
- 289
- 试验地点
- 1
- 主要终点
- HbA1c
研究概览
简要总结
To determine the effect of PF-00734200 on HbA1c in type 2 diabetic subjects receiving metformin
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men or women between 18-80 years of age with poorly controlled Type 2 diabetes
排除标准
- •Type 1 or secondary forms of diabetes Currently using insulin
研究组 & 干预措施
30 mg QD
Experimental
干预措施: PF-00734200 30 mg QD (Drug)
20 mg QD
Experimental
干预措施: PF-00734200 20 mg QD (Drug)
Placebo
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
HbA1c
时间窗: 12 weeks
次要结局
- Fasting Glucose(12 weeks)
- Fasting Insulin(12 weeks)
研究者
研究点 (1)
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