Androgen receptor in breast cancer - clinical and prognostic outcomes
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 96
- 试验地点
- 1
- 主要终点
- Incidence of androgen receptor in breast cancer in our population.
研究概览
简要总结
Patients with diagnosed breast cancer will be approached for participating in the study and will be explained the details of this study. Once patient agrees informed consent will be taken. The case will be recruited in the study and clinical history, examination, mammography report, tru cut IHC report will be collected. Post mastectomy specimen will be sent for immunohistochemistry staining, Generally we sent post mastectomy specimen for IHC staining of estrogen, progesterone receptors and HER2 neu receptors along with that androgen receptor staining will also be done. The incidence of expression of androgen receptors will find out , correlation of AR status with the staging of breast cancer and correlation of AR with other tumor markers we will find out.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- Female
入选标准
- •Patient undergoing surgery for breast cancer and specimen sent for IHC.
- •Patient who underwent trucut and sent for IHC.
- •All patients received treatment at KMC both for metastatic and non metastatic breast cancer.
- •Patients consenting to be part of study.
- •Patients above 18 years of age.
排除标准
- •Age below 18 years.
- •Patient not willing to participate in study.
- •Male breast carcinoma.
- •Other malignancy at the time of breast cancer diagnosis.
- •Prior chemotherapy.
- •Patient failing tofollow up.
结局指标
主要结局
Incidence of androgen receptor in breast cancer in our population.
时间窗: To asses the oncological outcomes, response to treatment. | The patient outcomes will be seen at 3rd month and 6th month of follow up
The correlation of Androgen receptors with other biomarkers.
时间窗: To asses the oncological outcomes, response to treatment. | The patient outcomes will be seen at 3rd month and 6th month of follow up
Prognosis and survival outcomes of the disease.
时间窗: To asses the oncological outcomes, response to treatment. | The patient outcomes will be seen at 3rd month and 6th month of follow up
The patient outcomes will be seen at 3rd month and 6th month of follow up
时间窗: To asses the oncological outcomes, response to treatment. | The patient outcomes will be seen at 3rd month and 6th month of follow up
次要结局
- To correlate the AR status with the staging of the breast cancer.(To asses the response to treatment response to treatment at 3rd & 6th month)
研究者
Dr. Kotha S L KamakshiPasyanthi
Kasturba Medical college and Hospital