Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Drug: Dexamethasone; Drug: Vitamin C

• Registration Number: NCT02799134
• Lead Sponsor: qinshaozheng

Brief Summary

CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11
• Study First Submitted: 2016-04-06
• Study First Submitted QC: 2016-06-09
• Study First Posted: 2016-06-14
• Primary Completion: 2017-04-10
• Study Completion: 2017-04-30
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-21
• Last Update Posted: 2022-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 67

Inclusion Criteria

• Healthy college students.

Exclusion Criteria

• Current or history of psychiatric or neurological illness.
• Current use of any medications.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
group1	Dexamethasone	take Dexamethasone at 22:00 on the first day, 0.5mg
group2	Vitamin C	take Vitamin C at 22:00 on the first day, 0.5mg
group3	Dexamethasone	take Dexamethasone at 15:00 on the second day, 0.5mg

Primary Outcome Measures

Name	Time	Method
Cortisol Awakening Response Level(nmol/L) after Taking Dexamethasone	one year	The dosage of Dexamethasone is 0.5mg.

Trial Locations

Locations (1)

Beijing Normal University; 🇨🇳 Beijing, Beijing, China