Effect of gum treatment on a acute phase protein and iron indices in periodontitis patients undergoing haemodialysis

Not Applicable

Completed

• Conditions: Health Condition 1: N186- End stage renal diseaseHealth Condition 2: null- Group I - Chronic Periodontitis under hemodialysis for less than a yearGroup II - Chronic Periodontitis under hemodialysis for more than a yearGroup III - Chronic Periodontitis

• Registration Number: CTRI/2017/12/010727
• Lead Sponsor: Sheethel Menon V

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-10-19
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

A. Group I: Renal patients undergoing haemodialysis for less than a year with chronic periodontitis

i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop).

ii. Patients with more than or equal to 20 teeth

iii. Patients with clinical bleeding on probing.

iv. Patients undergoing haemodialysis for atleast 3months and less than a year.

B. Group II: 20 renal patients undergoing haemodialysis for more than a year with chronic periodontitis

i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop).

ii. Patients with more than or equal to 20 teeth

iii. Patients with clinical bleeding on probing.

iv. Patients undergoing haemodialysis for more than a year.

C. Group III: 20 systemically healthy periodontitis patients

i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop).

ii. Patients with more than or equal to 20 teeth

iii.Patients with clinical bleeding on probing.

Exclusion Criteria

1.Individuals with uncontrolled hypertension inspite of medication

2.Edentulous patients

3.Smokers, alcoholics, pregnant women and lactating mothers.

4.Patients needing prophylactic antibiotic medication in association with periodontal probing.

5.Patients who had undergone periodontal treatment in the past 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) C reactive protein level <br/ ><br>2) Iron Indices - Serum Iron, Serum Ferritin, Total Iron binding capacityTimepoint: 1 month

Secondary Outcome Measures

Name	Time	Method
1) Plaque index <br/ ><br>2) Gingival Index <br/ ><br>3) Probing pocket depth <br/ ><br>4) Clinical Attachment levelTimepoint: 1 month