PRP in Recurrent Implantation Failure
- Conditions
- Health Condition 1: O090- Supervision of pregnancy with history of infertility
- Registration Number
- CTRI/2022/12/048264
- Lead Sponsor
- Indira IVF Hospital Pvt Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Age 25â??40 years.
2.Body mass index (BMI) 18.5 to 29.9 kg/m2.
3.RIF is defined as no evidence of Gestational sac in TVS after 6 wks of gestation after transfer of >= 3 high-quality embryos in at least 3 fresh or frozen transfer cycles in an age group of < 40 years
4.Grade of embryo 3/4/5/6/AA/AB/BA.
1.Presence of endocrine disorders (uncontrolled diabetes mellitus / hyperprolactinemia, thyroid dysfunction)
2.Previous major uterine surgery
3.Previous hysteroscopic adhesiolysis
4.Hydrosalpinx
5.Fibroid uterus type 0,1,2 as per FIGO classification
6.Any fibroid >3.5 cm
7.Adenomyosis.
8.Thrombocytopenia (total platelet count < 1.5 lacs/ dl).
9.Abnormal uterine cavity on Hysteroscopy.
10.The patient is unlikely to be available for follow-up as specified in the protocol.
11.Chronic Liver Pathology leading to impaired coagulation profile.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Implantation rateTimepoint: Six weeks after ET
- Secondary Outcome Measures
Name Time Method Biochemical pregnancyTimepoint: Four weeks after ET;Clinical PregnancyTimepoint: Six weeks after ET;DeliveryTimepoint: Twenty four weeks after ET;Live BirthTimepoint: Thirty six weeks after ET;Ongoing PregnancyTimepoint: Twelve weeks after ET