HIF-1 Alpha, VEGF and MMP-8 Levels in Peri-implant Crevicular Fluid of Smokers Versus Non Smokers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Measurement of levels of HIF-1 Alpha, VEGF and MMP-8 in peri-implant crevicular fluid
研究概览
简要总结
Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis
详细描述
Peri -implant crevicular fluid was obtained from seven smoker patients and then compared to peri-implant crevicular fluid from seven non smoker individuals.
The peri-implant crevicular fluid was obtained using periopaper strips then analyzed using ELISA kits of these markers; HIF-1 Alpha, VEGF and MMP-8
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Medically free patients
- •Individuals with restored implants placed one year or more before study enrollment
- •Both genders
- •Age range 20-50 years old
排除标准
- •Pregnant Females
- •Lactating females
结局指标
主要结局
Measurement of levels of HIF-1 Alpha, VEGF and MMP-8 in peri-implant crevicular fluid
时间窗: Baseline
Markers collected using periopaper strips
次要结局
未报告次要终点
研究者
Sarah Elkot
Lecturer of Oral Medicine, Periodontology and Diagnosis, Faculty of Oral and Dental Medicine, Future University in Egypt, Cairo, Egypt.
Future University in Egypt