Evaluation of the effect of ketamine and bupivacaine combination on shoulder pain after gallbladder surgery by laparoscopy

Phase 3

Conditions: Shoulder pain after laparoscopic surgery.
Pain, unspecified

Registration Number: IRCT20200513047418N1

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 90

Inclusion Criteria

elective laparascopic cholecystectomy
age 18 -65 year
weight 55-100 kg
The duration of surgery is less than two hours.
No neurovascular disease, coagulation disorders, cardiovascular disease • No history of ketamine and bupivacaine allergy
No history of abdominal surgery

Exclusion Criteria

use of alcohol, painkillers and anti-inflammatory and non-steroidal anti-inflammatory drugs
Having chronic pain unrelated to gallbladder disease
Dissatisfaction of the patient to continue participating in this study
he need for laparotomy during laparoscopy
having acute cholecystitis
People who could not understand VAS.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of shoulder pain after laparoscopic surgery on (Visual Analogue Scale). Timepoint: Two, four, six, eight hours after surgery. Method of measurement: Visual Analogue Scale(VAS).

Secondary Outcome Measures

Name	Time	Method
umber of heartbeats. Timepoint: An hour before surgery and in 2-4-6-8 hours after surgery. Method of measurement: By counting the number of pulses per minute that is recorded in the checklist.;Dosage of analgesics. Timepoint: 8 hours after surgery. Method of measurement: Using a syringe, it is registered in the checklist in milligrams.;The first time analgesics are needed. Timepoint: 8 hours after surgery. Method of measurement: It is registered in the checklist and based on the minute.;Nausea and vomiting. Timepoint: 2-4-6-8 hours after surgery. Method of measurement: View and ask .By options has and does not have in the checklist.;Hypotension, pressure drop above 20% initial value. Timepoint: An hour before surgery and two, four, six, eight hours after laparoscopic cholecystectomy. Method of measurement: By a sphygmomanometer.