The effects of intravenous perioperative ketamine for analgesia after spine surgery

Phase 3

• Conditions: Spine surgery is generally associated with intense pain in the postoperative period. In this period, adequate pain management has been seen to correlate well with improved functional outcomes.; perioperative, ketamine, spine surgery, pain management

• Registration Number: TCTR20201209002
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-09
• Study Completion: 2021-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

elective spine surgery patient under GA
age 18-75-year-old
ASA physical status I-III

Exclusion Criteria

Pregnancy, psychiatric problems, chronic alcoholism, drug abuse, allergy to ketamine or morphine, history of receiving strong opioids before surgery, inability to use PCA, and lack of communication ability.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Morphine consumption postoperative at 24 hour and at 48 hour milligram

Secondary Outcome Measures

Name	Time	Method
VAS score at resting and movement 1, 6, 12, 24, 48 hour. Numeric of pain score,adverse effects of ketamine and morphine 1, 6, 12, 24, 48 hour. percentage