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A Study to measure the effects of ketamine magnesium sulphate and both on pain after breast cancer surgery when given during surgery

Not Applicable
Conditions
Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
Registration Number
CTRI/2023/10/059068
Lead Sponsor
Dr Joe John Chirayath
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Electively posted cases for modified radical mastectomy.

2)ASA 1 and 2

Exclusion Criteria

1)Patients with history of drug allergy to any of studied drugs .

2)Patients with difficulty in communication and pregnancy.

3)Patients with significant liver renal and cardiac disease

4)Morbid obesity ( BMI >40)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess and compare the effects of intravenous administration of 0.3mg/kg ketamine ,30mg/kg magnesium sulphate and 0.3mg/kg ketamine and 30mg/kg magnesium sulphate on postoperative pain and analgesic requirements in postoperative patients undergoing Modified Radical mastectomy surgeryTimepoint: Every 4 hrly till upto 12hrs postoperative.
Secondary Outcome Measures
NameTimeMethod
Any incidence of adverse events like sedation,hallucinations, emergence delirium, nausea ,vomiting,arrhythmiasTimepoint: Every 4 hrly till up to 12 hrs postoperative.
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