S-ketamine for acute and chronic headache after brainsurgery
Recruiting
- Conditions
- Post operative craniotomy pain. postoperative painpost-craniotomy headachedrug resistant epilepsy temporal lobectomypost-operatieve hoofdpijncraniotomie pijnresistente epilepsie temporale lobectomie
- Registration Number
- NL-OMON24994
- Lead Sponsor
- Maastricht Universitair Medisch CentrumDepartment of Neurosurgery and Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 62
Inclusion Criteria
Age >18 years
- Elective resective surgery for drug-resistant temporal lobe epilepsy
Exclusion Criteria
- Declined informed consent
- Allergy to any of the trial medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoint is the total postoperative opioid consumption at the 7th postoperative day with interim measurements at 24, 48, 72 and 96 hours.
- Secondary Outcome Measures
Name Time Method Secondary endpoints are the postoperative pain scores (VAS+NRS), patient health-related quality of life, psychological parameters, length of hospital stay and adverse events.