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Clinical Trials/NCT04204746
NCT04204746
Completed
Not Applicable

The Effects of Different Fresh Gas Flows and Different Anesthetics on Airway Temperature and Moisture in Patients Who Underwent General Anesthesia

Selcuk University0 sites240 target enrollmentStarted: April 1, 2016Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
240
Primary Endpoint
Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.

Overview

Brief Summary

There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia. Different flow rates of fresh gas mixture are used in both the investigator's hospital and the experiences of the anesthesiologists. It is aimed to study the effects of different fresh gas flow rates on the rate of temperature and moisture of the airway of patients who underwent general anesthesia.

Detailed Description

Under physiological conditions, inhaled air is heated and humidified as it passes through the nose and upper airways until reaching the alveoli. This mechanism is bypassed by endotracheal intubation. Ventilation with dry and cold compressed gases leads to loss of water and heat from the respiratory tract. Drying of the respiratory tract can lead to destruction of the cilia and mucous membranes, resulting in decreased mucociliary transport and increased concentration of secretions.There is no definitive literature on fresh gas mix (oxygen + air) flow rates in patients under general anesthesia. This study aimed to investigate whether two fresh gas flow rates routinely employed in the authors' practice affected airway temperature and humidity.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients aged 18-65 years underwent general anesthesia -

Exclusion Criteria

  • admitted to emergency and trauma, history of advanced cardiac disease, cigarette use ≥ 3 packet/day, pulmonary parenchymal disease such as malignancy or chronic obstructive pulmonary disease (COPD), history of thyroid disease, body mass index (BMI) greater than 30 kg/m2, alcohol and substance addiction, mentally deficiency, pregnancy or postpartum, fever and infection, drug use such that would influence thermoregulation such as vasodilators, hemorrhage \> 5 mL/kg, and patients who declined to participate.

Outcomes

Primary Outcomes

Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.

Time Frame: 2016-2018

We will evaluate if different fresh gas flows effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.

Secondary Outcomes

  • Affect of different anesthetic gases (sevoflurane, desflurane) and drugs (propofol)on patients' airway temperature and humidity.(2016-2018)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ozkan Onal

Professor

Selcuk University

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