The Effects of Different Fresh Gas Flows and Different Anesthetics on Airway Temperature and Moisture in Patients Who Underwent General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 主要终点
- Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.
研究概览
简要总结
There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia. Different flow rates of fresh gas mixture are used in both the investigator's hospital and the experiences of the anesthesiologists. It is aimed to study the effects of different fresh gas flow rates on the rate of temperature and moisture of the airway of patients who underwent general anesthesia.
详细描述
Under physiological conditions, inhaled air is heated and humidified as it passes through the nose and upper airways until reaching the alveoli. This mechanism is bypassed by endotracheal intubation. Ventilation with dry and cold compressed gases leads to loss of water and heat from the respiratory tract. Drying of the respiratory tract can lead to destruction of the cilia and mucous membranes, resulting in decreased mucociliary transport and increased concentration of secretions.There is no definitive literature on fresh gas mix (oxygen + air) flow rates in patients under general anesthesia. This study aimed to investigate whether two fresh gas flow rates routinely employed in the authors' practice affected airway temperature and humidity.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18-65 years underwent general anesthesia -
排除标准
- •admitted to emergency and trauma, history of advanced cardiac disease, cigarette use ≥ 3 packet/day, pulmonary parenchymal disease such as malignancy or chronic obstructive pulmonary disease (COPD), history of thyroid disease, body mass index (BMI) greater than 30 kg/m2, alcohol and substance addiction, mentally deficiency, pregnancy or postpartum, fever and infection, drug use such that would influence thermoregulation such as vasodilators, hemorrhage > 5 mL/kg, and patients who declined to participate.
结局指标
主要结局
Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.
时间窗: 2016-2018
We will evaluate if different fresh gas flows effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.
次要结局
- Affect of different anesthetic gases (sevoflurane, desflurane) and drugs (propofol)on patients' airway temperature and humidity.(2016-2018)