Health effects of Sustainable future Proteins

Completed

• Conditions: darm gezondheid (geen aandoeningen) en vertering; digestion; intestinal permeability

• Registration Number: NL-OMON46301
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 36

Inclusion Criteria

-Age between 35-70y
-BMI between 18 - 30kg/m2

Exclusion Criteria

- - Intake of medications known to change the inflammatory status (including proton pump inhibitors, anti-inflammatory medication (including NSAIDs)
- Having a history of medical or surgical events that may significantly affect the study outcome
- Kidney dysfunction (self-reported)
- Gastrointestinal disorders, constipation (defecation <3 times a week) or history of gastrointestinal surgery
- Allergies for our intervention products
- Recent use of antibiotics (<1 month prior to day 01 of the study)
- Not having a general practitioner
- Mental status that is incompatible with the proper conduct of the study
- Pregnancy or lactating
- Reported weight loss or weight gain of > 5 kg in the month prior to pre-study screening
- Reported slimming, medically prescribed, other (extreme) diet, or use of protein concentrates
- Not willing to give up blood donation during the study
- Current smokers
- Alcohol intake > 3 glasses per day
- Hard-drug abuse
- Participation in other clinical trials in the past month
- Being an employee (or student) of the department Consumer Science & Health group of Wageningen Food & Biobased Research
Additional exclusion for participation in the postprandial study:
- Having blood vessels that are too difficult for inserting a cannula
- Anaemia (Hb values <7.5 for women and < 8.5 for men)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is to assess the degree of digestibility and<br /><br>protection of the epithelial barrier/ gut permeability.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters include other markers of gastrointestinal health,<br /><br>metabolic health, vascular health and satiating properties.</p><br>