RAR-CLA and cognitio
- Conditions
- cognitive impairment
- Registration Number
- NL-OMON29637
- Lead Sponsor
- Stepan Specialty Products B.V.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 52
• Aged =65 years
• At risk of cognitive impairment/ memory complaints
• Able to understand and perform the study procedures
• Body Mass Index (BMI) >35 kg/m2
• Current use of medication belonging to the sartans” or glitazones”
• Current use of >500 mg/day of acetylsalicylic acid
• Current use of medication that affects inflammation (anti-inflammatory medication)
• Fish consumption of more than 1 serving per week
• Current or recent (<1 month) use of fish oil supplements
• Current or recent (<1 month) use of anti-inflammatory dietary supplements such as quercetin, curcumin, resveratrol, and/or other flavonoids
• Diabetes mellitus
• Having a disease which interferes with the effect of the RAR-CLA supplement and/or with the outcome measure (cognitive functioning) as judged by medical doctor
• Swallowing problems
• Current participation in other scientific research with the exception of EetMeetWeet!
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Episodic memory as measured with the RAVLT
- Secondary Outcome Measures
Name Time Method cognitive functioning (episodic and working memory, attention, executive functioning, and psychomotor speed) as measured with a battery of cognitive tests, the evaluation of rumenic acid supplementation on anxiety, depressive symptoms, quality of life (measured with questionnaires), and plasma fatty acid status (measured in blood)