Study for the regulation mechanism of acupuncture on brain-gut in patients with migraine

Not Applicable

Recruiting

• Conditions: migraine without aura

• Registration Number: ITMCTR1900002521
• Lead Sponsor: Chengdu University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Right hand; aged between 18-55 years, gender is not limited;
2. Education time >= 6 years;
3. Meet the above-mentioned IHS diagnostic criteria for aura without migraine;
4. There is a history of migraine for more than 1 year. The migraine first started before the age of 50. In the past 1 month and the baseline period, the average headache occurred 2-6 times per month;
5. BAI standard scores is less than 36 points, and BDI standard scores is less than 21 points;
6. The patient signed the informed consent form.

Exclusion Criteria

1. Patients with a history of head trauma, secondary headache, tension headache, intermittent headache, cluster headache and cardiovascular disease, digestive system diseases;
2. Those who have experienced major bowel resection or major gastrointestinal surgery in the past;
3. Mental patients, susceptible to infection and bleeding, allergies;
4. Pregnant women and lactating women;
5. Can not understand or record the headache diary;
6. Suffering from moderate constipation and diarrhea in the past 3 months;
7. In the past 1 month, he received medical treatment for cholecystitis, peptic ulcer, urinary tract infection, acute pyelonephritis, cystitis;
8. Antibiotics have been used in the past 3 months for 3 days or more; or have long-term use of drugs such as analgesics;
9. Received acupuncture or other preventive treatment in the past 3 months;
10. There are metal implants in the body, and other MRI examination contrabands such as claustrophobia;
11. In the MRI scan, severe head anatomical structures were found to be asymmetric or have clear lesions;
12. Patient has participated in similar researchers within 3 months.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HIT-6;GSRS;headche diary;Intestinal flora data collection and processing;fMRI;SF-MPQ;

Secondary Outcome Measures

Name	Time	Method
MMSE;BDI;SF-36;BAI;