Study on the regulation mechanism of acupuncture on sex hormones in patients with POI based on metabonomics

Phase 1

Recruiting

• Conditions: premature ovarian insufficiency

• Registration Number: ITMCTR2100005106
• Lead Sponsor: The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

(1) meeting the diagnostic criteria of Poi;
(2) 18 to 40 years of age;
(3) no other treatment for 2 months before admission;
(4) patients participated in this study voluntarily and actively participated in the trial;
(5) signed consent form; Those who met the above 6 criteria were included in the study.

Exclusion Criteria

(1) congenital abnormalities of the reproductive organs; Polycystic Ovary Syndrome; Hyperprolactinaemia, pituitary or Hypothalamus Amenorrhea and thyroid dysfunction; congenital malformation of the reproductive organs and organic lesions;
(2) history of local ovarian surgery, for example, after ovariectomy, ovarian tumor operation, history of chemotherapy or pelvic radiotherapy, history of immunosuppressive therapy;
(3) complicated with serious diseases of cardiovascular system, liver, kidney, hematopoiesis system, nervous and mental system, diabetes and hypertension;
(4) could not tolerate blood or ultrasound examination and acupuncture treatment in the course of this study;
(5) failure to complete the total number of acupuncture treatments;
(6) refusal to sign the informed consent form;

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antimullerian hormone;

Secondary Outcome Measures

Name	Time	Method
antral follicle count;three sex hormones;