The mechanism study of acupuncture intervention in migraine patients based on the technology of magnetic resonance spectroscopy and metabolomics
- Conditions
- Migraine
- Registration Number
- ITMCTR2000003293
- Lead Sponsor
- Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Patients with right handedness;
2. Patients with migraine without aura;
3. Patients aged 18-55 years;
4. Patients with headache attack times >=2 times per month in the past 3 months;
5. Patients with a course of >=1 year;
6. Patients without Mrs test contraindications;
7. Patients without long-term habit of taking analgesics did not take psychoactive drugs in the past 3 months or vasoactive drugs in the past two weeks;
8. Patients who sign informed consent.
1. The first attack of migraine was after 50 years old;
2. Patients with history of head injury, secondary headache, tension headache, intermittent headache, cluster headache, etc;
3. Patients with cardiovascular, hypertension, digestive, hematopoietic system, liver, kidney and other serious primary diseases;
4. Patients with psychosis, allergic constitution, easy to combine infection and bleeding;
5. Patients taking migraine prevention drugs in recent four weeks;
6. Pregnant women and lactating women;
7. Patients who can't understand the cooperation examination or other MRI taboos such as claustrophobia;
8. In the MRI scan, the patients with serious head anatomical structure asymmetry or definite lesions were found.
Study & Design
- Study Type
- Basic Science
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Magnetic resonance spectrum data;Metabolomic data;
- Secondary Outcome Measures
Name Time Method Quality of Life;Days of migraine attack;Intensity of migraine;Sleep quality;Frequency of migraine attacks;