Evaluation of Intestinal Parasites in Patients With Intestinal Cancer in Sohag, Egypt.

Recruiting

• Conditions: Intestinal Parasites in Patients With Intestinal Cancer
• Interventions: Diagnostic Test: stool examination

• Registration Number: NCT05850884
• Lead Sponsor: Sohag University

Brief Summary

This study aims to evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals

Detailed Description

Intestinal parasitic infections continue to be characterized as a significant cause of morbidity worldwide, and according to World Health Organization (WHO) statistics, more than a quarter of the world's population, mostly in developing countries, are infected Acquisition of infection, clinical severity, and outcome of a parasitic disease depend on innate and acquired host immunity as well as on the parasite's response against the host when the infection is established Chronic infections and inflammation along with unhealthy diet, stressful lifestyle, cell damage, constant exposure to radiation, and harmful chemicals are risk factors for the development of cancers As infectious factors, the Blastocystis hominis and Cryptosporidium spp. are opportunistic protozoa isolated from the human host gastrointestinal tract, These prevalent enteric parasites may cause serious challenges in people undergoing colorectal cancer treatment (chemotherapy)

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2023-04-30
• Study First Submitted QC: 2023-04-30
• Study First Posted: 2023-05-09
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-24
• Last Update Posted: 2023-11-27
• Study Start: 2023-11-30
• Primary Completion: 2024-04-30
• Study Completion: 2024-05-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• intestinal cancer patients (colorectal cancer, intestinal lymphoma, gastrointestinal stromal tumors, and other malignant variants)

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Exclusion Criteria

• patient took antibiotics within the previous four weeks and anti-parasitic drugs within the previous two weeks

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group B	stool examination	one hundred stool samples will be collected from the control group of patients who attended outpatient clinics
group A	stool examination	• One hundred stool samples will be collected from patients with intestinal cancer admitted to Sohag Hospital.

Primary Outcome Measures

Name	Time	Method
evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals	12 months	• Each collected sample will be divided into three parts; 1st part will be examined freshly without preservatives by macroscopic and microscopic examination, the 2nd part will be preserved for concentration techniques, staining, and microscopic examination and the 3rd part will be cultivated for Strongyloides stercoralis diagnosis

Trial Locations

Locations (1)

Sohag University; 🇪🇬 Sohag, Egypt