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临床试验/NCT05850884
NCT05850884招募中不适用

Evaluation of Intestinal Parasites in Patients With Intestinal Cancer in Sohag, Egypt.

Sohag University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年11月30日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
100
试验地点
1
主要终点
evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals

研究概览

简要总结

This study aims to evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals

详细描述

Intestinal parasitic infections continue to be characterized as a significant cause of morbidity worldwide, and according to World Health Organization (WHO) statistics, more than a quarter of the world's population, mostly in developing countries, are infected Acquisition of infection, clinical severity, and outcome of a parasitic disease depend on innate and acquired host immunity as well as on the parasite's response against the host when the infection is established Chronic infections and inflammation along with unhealthy diet, stressful lifestyle, cell damage, constant exposure to radiation, and harmful chemicals are risk factors for the development of cancers As infectious factors, the Blastocystis hominis and Cryptosporidium spp. are opportunistic protozoa isolated from the human host gastrointestinal tract, These prevalent enteric parasites may cause serious challenges in people undergoing colorectal cancer treatment (chemotherapy)

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

年龄范围
2 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • intestinal cancer patients (colorectal cancer, intestinal lymphoma, gastrointestinal stromal tumors, and other malignant variants)

排除标准

  • patient took antibiotics within the previous four weeks and anti-parasitic drugs within the previous two weeks

结局指标

主要结局

evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals

时间窗: 12 months

• Each collected sample will be divided into three parts; 1st part will be examined freshly without preservatives by macroscopic and microscopic examination, the 2nd part will be preserved for concentration techniques, staining, and microscopic examination and the 3rd part will be cultivated for Strongyloides stercoralis diagnosis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nagwa Ibrahim Selim

Teaching Assistant

Sohag University

研究点 (1)

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