Concomitant Infection of Intestinal Parasites and Helicobacter Pylori in Sohag University Hospital
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Sohag University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital
Study Overview
Brief Summary
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in the world especially in developing countries.
Helicobacter pylori is a gram-negative,helical-shaped,motile bacillus bacterium,which colonizes the gastric mucosa.
H.pylori bacterium secretes urease,a special enzyme that converts urea to ammonia.
Ammonia reduces the stomach's acidity .This risk factor allows pathogenic intestinal protozoa such as G.lamblia to take the opportunity to cross through the stomach's increased pH and cause disease.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 1 Year to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •patients complaining of dyspepsia , abdominal burning pain,diarrhea,dysentery,of persons of any age or sex group.
Exclusion Criteria
- •patients taking antibiotics within the previous four weeks, proton pump inhibitors within the previous two weeks, or anti-parasitic drugs within the previous two weeks.
Outcomes
Primary Outcomes
Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital
Time Frame: 18 weeks following the start point of the study
Collection of 200 stool samples (100 positive and 100 negative for H.pylori) then parasitological examination done for all samples
Secondary Outcomes
- Evaluate the prevalence of intestinal parasitic infection among H.pylori infected outpatients in Sohag University Hospital(18 weeks following the start point of the study)
Investigators
Asmaa Nabil Abouzeid
Demonstrator at medical parasitology department at faculty of medicine Sohag university
Sohag University