Concomitant Infection of Intestinal Parasites and Helicobacter Pylori

• Conditions: Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
• Interventions: Diagnostic Test: H.pylori stool antigen rapid test and stool parasitological examination

• Registration Number: NCT05360940
• Lead Sponsor: Sohag University

Brief Summary

Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in the world especially in developing countries.

Helicobacter pylori is a gram-negative,helical-shaped,motile bacillus bacterium,which colonizes the gastric mucosa.

H.pylori bacterium secretes urease,a special enzyme that converts urea to ammonia.

Ammonia reduces the stomach's acidity .This risk factor allows pathogenic intestinal protozoa such as G.lamblia to take the opportunity to cross through the stomach's increased pH and cause disease.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2022-05-01
• Study First Submitted QC: 2022-05-01
• Study First Posted: 2022-05-04
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-18
• Last Update Posted: 2022-07-19
• Study Start: 2022-09
• Primary Completion: 2023-02
• Study Completion: 2023-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• patients complaining of dyspepsia , abdominal burning pain,diarrhea,dysentery,of persons of any age or sex group.

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Exclusion Criteria

• patients taking antibiotics within the previous four weeks, proton pump inhibitors within the previous two weeks, or anti-parasitic drugs within the previous two weeks.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
A	H.pylori stool antigen rapid test and stool parasitological examination	100 positive stool samples for H.pylori
B	H.pylori stool antigen rapid test and stool parasitological examination	100 negative stool samples for H.pylori

Primary Outcome Measures

Name	Time	Method
Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital	18 weeks following the start point of the study	Collection of 200 stool samples (100 positive and 100 negative for H.pylori) then parasitological examination done for all samples

Secondary Outcome Measures

Name	Time	Method
Evaluate the prevalence of intestinal parasitic infection among H.pylori infected outpatients in Sohag University Hospital	18 weeks following the start point of the study	Macroscopic and microscopic examination of 100 positive H.pylori stool samples

Trial Locations

Locations (1)

Asmaa Nabil Abouzeid; 🇪🇬 Sohag, Egypt