Effects of Sufentanil on the Intraoperative Hemodynamics
Not Applicable
Recruiting
- Conditions
- Intraoperative Hypotension
- Interventions
- Registration Number
- NCT06091904
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
- Patients who undergo elective extracranial-intracranial bypass surgery
- American Society of Anesthesiologists grade 1,2,3
- Age > 18 years old
Exclusion Criteria
- Refuse to participate to the study
- American Society of Anesthesiologists grade 4
- Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
- Allergic history of opioid
- pregnant
- MAO Inhibitor user
- Severe respiratory insufficiency
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description sufentanil group Sufentanil sufentanil is administered for analgesic during general anesthesia remifentanil group Remifentanil remifentanil is administered for analgesic during general anesthesia
- Primary Outcome Measures
Name Time Method Intraoperative hypotension During surgery Target systolic blood pressure \< 90%
- Secondary Outcome Measures
Name Time Method Incidence of tachycardia During surgery heart rate \> 100/min
Incidence of bradycardia During surgery heart rate \< 40/min
Minimum systolic blood pressure During surgery minimal systolic blood pressure
Inotropic requirements During surgery cumulative doses of inotropics during surgery
Maximum systolic blood pressure During surgery maximal systolic blood pressure
Trial Locations
- Locations (1)
Seoul National University Bundang Hospital
🇰🇷Seongnam-si, Gyeonggi-do, Korea, Republic of