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Clinical Trials/NCT05315037
NCT05315037
Recruiting
Not Applicable

Resistance Training Methods Impact On Glycemic Excursion and Metabolic Pathways in Type 1 Diabetes Mellitus

University of Louisville2 sites in 1 country15 target enrollmentAugust 1, 2023
ConditionsType 1 Diabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 1 Diabetes
Sponsor
University of Louisville
Enrollment
15
Locations
2
Primary Endpoint
Assess glucose response to different resistance training methods
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to learn how different resistance training programs affects blood sugar in young athletes with T1DM.

Detailed Description

Strength and condition training to improve sport performance has been greatly emphasized over the past 20 years. Formal strength and conditioning (S\&C) programming is performed by S\&C coaches who are educated in the field of exercise program with the intentions to bring about particular athletic adaptations through exercise. S\&C programs, previously limited to programs at the college and professional level, are now commonly seen in secondary school athletic programs. With such broad adoption, many athletes that manage chronic diseases, such as type 1 diabetes mellitus, are exposed to elements of these programs. Diabetes mellitus impacts more than 10% of the United States population. Of these, 5.2% have identified type 1 diabetes mellitus (T1DM) which includes approximately 210,000 individuals under the age of 20. In addition to insulin and dietary management, exercise and physical activity is recommended as an important therapeutic tool for most patients with T1DM. Physical activity has been shown to significantly improve glycemic control in individuals with diabetes. Additional benefits of exercise include improved cardiovascular fitness, muscle strength, insulin sensitivity and blood glucose control. S\&C programs offer benefits to those living with T1DM as different exercises can be tailored to preserve health. However, there are no exercise prescription or guidelines specifically for adolescent athletes diagnosed with type 1 diabetes participating in strength and conditioning programs. Furthermore, there is no available data that states the predictability of glucose response and insulin needs to any of the specific strength and conditioning goals. Objective: To assess the impact of different strength and conditioning programming on glycemic control in athletes with T1DM. Primary Aim: Assess glucose response to different resistance training methods. Secondary Aims: To assess for correlation between lactate and glucose using different resistance training methods.

Registry
clinicaltrials.gov
Start Date
August 1, 2023
End Date
December 30, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Bradly Thrasher

Assistant Professor

University of Louisville

Eligibility Criteria

Inclusion Criteria

  • ≥ 13 years of age
  • ≥2 years from date of T1DM diagnosis
  • Prior exposure to strength and conditioning
  • HbA1C ≤ 10%
  • Actively utilizing continuous glucose monitoring for diabetes management

Exclusion Criteria

  • Physical limitation that may impede ability to complete study procedures
  • Non-English-speaking individual

Outcomes

Primary Outcomes

Assess glucose response to different resistance training methods

Time Frame: 3 months

Blood glucose

Secondary Outcomes

  • To assess for correlation between lactate and glucose using different resistance training methods(3 months)

Study Sites (2)

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