Comparing Hyperbaric Levobupivacaine and Hyperbric Ropivacaine as spinal anesthetic drugs for elective lower limb orthopedic surgeries.
Phase 4
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: M971- Periprosthetic fracture around internal prosthetic knee joint
- Registration Number
- CTRI/2023/08/056435
- Lead Sponsor
- Dr Rajendra Prasad Government Medical college KANGRA at TANDA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients with Body Mass Index (BMI) between 18 -29.9 kg/m2.
2)ASA I and II patients scheduled for elective lower limb orthopaedic surgery with anticipated
duration of surgery between 120 - 180 mins
Exclusion Criteria
1. Patients refusal for central neuraxial block.
2. Patients with BMI more than 30.
3. Patients allergic to the drugs under consideration.
4. Patients having absolute contraindication for spinal anaesthesia.
5. Primary or metastatic malignancy.
6. Patients with deformity of spine where drug spread is unpredictable.
7. Partial effect or failed spinal.
8. Patients in which space other than L3-L4 inter-vertebral space is used for instituting spinal.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method efficacy of the two drugs hyperbaric Levo-bupivacaine & hyperbaric Ropivacaine in subarachnoid block in terms of sensory and motor block characteristics.Timepoint: time required for onset and regression of sensory and motor blockade. <br/ ><br>sensory and motor block at 20 minutes
- Secondary Outcome Measures
Name Time Method Post operative haemodynamic parametersTimepoint: haemodynamic monitoring at 0,15,30,45,60,75,90,105,120,135,150,165,180,195,210,225,240 minutes;To study effect of drug on intra operative hemodynamic parameters of the patient, total vasopressor requirement between two groups & side effect of drug used if any.Timepoint: Hemodynamic parameters at 0, 3,6,9,12,15,20,25,30,35,40,45,50,55,60,65,70,75,80,85,90,95,100,105,110,115,120,125,130,135,140,145,150,155,160,165 minutes