NL-OMON45142招募中3 期
Prophylactic Cranial Irradiation with or without hippocampal avoidance in SCLC: a randomized phase III study - HA-PCI
ederlands Kanker Instituut0 个研究点目标入组 125 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 125
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* SCLC patients (stage I-III or stage IV without clinical or radiological evidence of brain metastases) candidate for PCI, i.e. without progressive disease after chemo-radiotherapy in stage I-III or after a remission after chemotherapy in stage IV
- •* WHO-performance status * 2(see Appendix IV).
- •* Sufficient proficiency in Dutch language
- •* Written informed consent must be given according to ICH/GCP, national and local regulations
排除标准
- •* Prior radiotherapy to the brain
- •* clinical evidenceof brain metastases or primary brain tumors
- •* Evidence of progressive extracranial metastatic disease
- •* Previous malignancy < 2 years ago except for adequately treated basal cell carcinoma of the skin and carcinoma in situ of the cervix
- •* Any systemic anticancer treatment during PCI or within 3 weeks before start PCI.
- •* Pregnancy or lactation
研究者
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