Effects of Melothria maderaspatana (Titta kekiri) and Passiflora foetida (Dal batu) dry fruit preparation (topical application) on renal functions of Grade II and III Chronic Kidney Disease (of unknown etiology) patients in North central Province, Sri
- Conditions
- Chronic Kidney Disease (of unknown etiology)
- Registration Number
- SLCTR/2011/005
- Lead Sponsor
- Faculty of Medicine University of Rajarata
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 35
a)Diagnosed patients of having grade II and III CKDu, Normal HbA1C (?6.5%) and BP?160/100 mmHg untreated or ?140/90 mmHg on up to two antihypertensive agents, Persistent albuminuria + eGFR 30- 89 mi/min/1.73m2
b)Age between 20-60 years
c)Permanent residents of Anuradhapura or Polonnaruwa district, for at least 5 years prior to diagnosis as Grade II or III CKDu
a)Patients with no past history of or current treatment for diabetes mellitus or chronic and/or severe hypertension, snakebite, urological disease of known etiology or glomerulonephritis
b)Patients who are suffering with other chronic diseases or on treatment for any other disease other than CKDu
c)Patients aged less than 20 years and more than 65 years
d)Pregnant and breast feeding mothers
e)Patients who live outside the NCP,are not permanent resident within NCP at least 5 years prior to diagnose as CKDu and residents in GN divisions where WHO is conducting the Study for CKDu
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Full blood count [10 months]<br>Lipid profile<br> [10 months ]<br>Renal profile<br> [10 months ]<br>Liver enzymes-SGPT and SGOT [10 months ]<br>Urine full report including ß2 globulin level [10 months ]<br>IFNd [10 months ]<br>TNFa [10 months ]<br>HSP70 [10 months ]<br>
- Secondary Outcome Measures
Name Time Method one [None]<br>