Plasma Immunity of Mild SARS-CoV-2 Omicron and Delta Pandemic in Thailand

Completed

• Conditions: COVID-19

• Registration Number: NCT05328479
• Lead Sponsor: Mahidol University

Brief Summary

The investigators assessed the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation.

Detailed Description

The investigators aimed to assess the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation. The investigators compared the population between the age groups 12-18 years, 18-45 years and over 45 years to monitor the symptoms of coronavirus patients treated in home isolation and long-term symptoms including factors related to the patient's recovery in the past, present, and future.

Study Timeline

• Study Start: 2021-11-04
• Primary Completion: 2022-03-15
• Study First Submitted: 2022-04-07
• Study First Submitted QC: 2022-04-07
• Study First Posted: 2022-04-14
• Study Completion: 2022-05-20
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-17
• Last Update Posted: 2022-10-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5181

Inclusion Criteria

1. patient with infected with the novel coronavirus disease 2019 (COVID-19) who has been end of self-quarantine at Siriraj Hospital more than 21 days.
2. Thai nationality, able to read and write Thai language
3. able to use telephone and line to communicate

Exclusion Criteria

1. people who received additional vaccination after leaving quarantine before the day of the immunization test

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anti-SARS-CoV-2 RBD IgG	Baseline	Anti-RBD IgG (BAU/mL)
Cycle threshold of the first PCR test	Baseline	Cycle threshold (Ct)
Anti-SARS-CoV-2 NP	Baseline	Anti-SARS-CoV-2 NP (PRNT50 titer)

Secondary Outcome Measures

Name	Time	Method
Type of vaccine injection	Baseline	Type of vaccine injection
Number of vaccine injection	Baseline	Number of vaccine injection

Trial Locations

Locations (1)

Faculty of Medicine Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok Noi, Bangkok, Thailand