Calcium supplementation during pregnancy in low-intake populations

Not Applicable

Completed

• Conditions: Pre-eclampsia; Pregnancy and Childbirth

• Registration Number: ISRCTN37214165
• Lead Sponsor: DP/UNFPA/WHO/World Bank - Special Programme of Research, Development and Research Training in Human Reproduction

Brief Summary

2006 Results article in http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16522392

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2003-06-01
• Study Start: 2004-04-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 8325

Inclusion Criteria

1. Nulliparous pregnant women less than 20 weeks gestation
2. Living in low calcium intake areas

Exclusion Criteria

1. The presence of blood pressure greater than 140 and/or 90 mmHg at first antenatal visit
2. A history of chronic hypertension or renal disease
3. A history or signs and/or symptoms of nephrolithiasis, parathyroid disorders, and diseases that require digoxin, phenytoin, or tetracycline therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Primary maternal outcome: incidence of preeclampsia and/or eclampsia<br> 2. Primary neonatal outcome: preterm delivery<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Early preterm delivery (less than 32 weeks of gestation)<br> 2. Term low birth weight (less than 2500 g; greater than or equal to 37 weeks of gestation)<br> 3. Hospitalisation of greater than 2 days<br> 4. Greater than or equal to 7 days in the neonatal intensive care unit<br> 5. Foetal, neonatal, and perinatal death<br>