Acute uncomplicated appendicitis in children - Is surgery the preferred option?
- Conditions
- Health Condition 1: null- Acute Non-Perforated Appendicitis in Children
- Registration Number
- CTRI/2018/01/011088
- Lead Sponsor
- All India Institute of Medical Sciences Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Age between 3 to 14 years both male and female.
2.Symptoms of Pain Abdomen, Anorexia, Nausea, Vomiting, Fever.
3.Signs of Focal Peritonitis (Guarding, Rebound tenderness) in Right Iliac Fossa (RIF).
4.Laboratory Findings of â?? Total Leukocyte Count, â?? Neutrophil count, â?? CRP, â?? LRG.
5.Abdominal Ultrasonogram s/o noncompressible nonperistaltic tubular structure >= 6 mm in AP diameter in RIF, probe tenderness in RIF, hyperechoic pericaecal fat & free fluid.
6.Abdominal CT scan suggestive of acute nonperforated appendicitis
1.History of Recurrent Appendicitis
2.History of Chronic , Intermittent abdominal pain
3.Diffuse abdominal tenderness on clinical evaluation
4.Generalized Septicemia , Other Systemic illnesses
5.Abdominal Ultrasonography s/o Appendicolith, Appendicular Perforation ,Periappendicular Abscess or Phlegmon , Pan-peritonitis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The feasibility and safety of the Conservative Management (CMx) with Antibiotics in children with acute Nonperforated Appendicitis.Timepoint: 1st Month - Feasibility assessment <br/ ><br>6th Month - Mid-recruitment review <br/ ><br>1 year - Final assessment.
- Secondary Outcome Measures
Name Time Method a)Length of Stay in the Hospital <br/ ><br>b)Cost of Treatment <br/ ><br>c)Perforation Rate in CMx group <br/ ><br>d)Lump formation in CMx group <br/ ><br>e)Appendicular Abscess in CMx group <br/ ><br>f)Intraoperative Complications in SMx group <br/ ><br>g)Wound Complications in SMx group <br/ ><br>h)Negative Appendectomy Rate in SMx group <br/ ><br>i)Disability Days for the Child and Parents <br/ ><br>j)Missed School Days <br/ ><br>k)Measures of Quality of Life (PedsQLTM survey) <br/ ><br>l)Health Care Satisfaction (1 to 10 score) <br/ ><br>m)Recurrence Rate of Appendicitis in CMx groupTimepoint: All the children enrolled in the CMx group will be called / telephoned for follow up at 1 month, 3 months and 1 year interval.