Effectiveness and Safety of Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis

• Conditions: ncomplicated acute appendicitis; K35.8; Acute appendicitis, other and unspecified

• Registration Number: DRKS00010401
• Lead Sponsor: niversitätsklinikum Mannheim

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-05-24
• Study Completion: 2018-06-26
• Results First Posted: 2019-09-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 134

Inclusion Criteria

Patients aged 18 years or older admitted to the emergency department with a clinical suspicion of uncomplicated acute appendicitis. After decision for the conservative antibiotic therapy (by the surgeon and patient) all patients have to give written informed consent to participate in the study.

Exclusion Criteria

Patients who are not sufficiently compliant to ensure a follow-up of 12 months.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Successful antibiotic treatment of appendicitis, defined as non-requirement of appendectomy within the follow-up period of one and a half years.

Secondary Outcome Measures

Name	Time	Method
ength of hospital stay, Pain scores (using a visual analog scale, VAS), length of sick leave from work, complications (using the Clavien- Dindo- Classification).