Randomised trial of anti-emetics in pre-hospital care (The RAPS Trial)
Phase 4
- Conditions
- ausea and vomitingNausea and vomitingOther - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)
- Registration Number
- ACTRN12608000576325
- Lead Sponsor
- St John Ambulance - Western Australian Ambulance Service
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
All patients managed by the ambulance service who are either actively vomiting or have a nausea score greater or equal to 4
Exclusion Criteria
Age less than 18
Received trial agents in the previous 24hours
Pregnant or possibly pregnant
Weight less than 60kg
Altered conscious level (Glascow Coma Score < 15)
Refuses intramuscular injection
No consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in nausea and vomiting. <br>Active vomiting will be assessed by direct observation of the patient. <br>Nausea will be assessed using a verbal analogue scale (Rating scale of 1 - 10).[On arrival at hospital Emergency Departments]
- Secondary Outcome Measures
Name Time Method Significant adverse events will be assessed through either direct observation by the attending ambulance paramedic or observed / reported by clinical staff at the receiving hospital.[On arrival at hospital Emergency Departments]