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Clinical Trials/NCT04818021
NCT04818021TerminatedNot Applicable

Contribution of the Somatosensory System to Speech Perceptual Processing Aim 3

Yale University1 site in 1 country30 target enrollmentStarted: August 1, 2019Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Terminated
Enrollment
30
Locations
1
Primary Endpoint
Mean Change in Perception Judgement

Study Overview

Brief Summary

These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.

Detailed Description

This study will assess changes to the perceptual classification of speech sounds that are related to repeated pairing of somatosensory and auditory inputs (as would occur during speech motor learning). Before and after the training, base-line and post-training auditory perceptual performance will be examined in the absence of somatosensory stimulation, in order to evaluate the effects of the pairing on speech perception. Perceptual classification will be assessed on a 7 point continuum.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Basic Science
Masking
None

Eligibility Criteria

Ages
21 Years to 40 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •right handed adults
  • •no known physical or neurological abnormalities

Exclusion Criteria

  • •patients with:
  • •cardiac pacemaker
  • •surgical clips or values on the heart
  • •metal or metallic fragments in any part of the body
  • •pregnancy
  • •claustrophobia
  • •a personal or family history of epilepsy
  • •currently taking antipsychotic drugs
  • •currently taking antidepressant drugs
  • •currently taking antianxiety drugs.

Arms & Interventions

Perceptual Judgement with Skin Stretch

Experimental

Perceptual Judgement with Skin Stretch

Intervention: Perceptual Classification of Speech Sounds (Behavioral)

Perceptual Judgement with Skin Stretch

Experimental

Perceptual Judgement with Skin Stretch

Intervention: Facial Skin Stretch (Behavioral)

Perceptual Judgement Control without Skin Stretch

Experimental

Perceptual Judgement Control without Skin Stretch

Intervention: Perceptual Classification of Speech Sounds (Behavioral)

Outcomes

Primary Outcomes

Mean Change in Perception Judgement

Time Frame: Baseline and at the end of training (30 minute session)

Change in perceptual threshold of which words participants heard when presented with different options on a synthetic acoustic 7 point interval scale continuum. Higher means indicate a greater change in auditory perception following the pairing of sounds and facial skin stretch. Score range 0-7

Speech Motor Learning

Time Frame: Performance as measured at the end of learning (30 minute session)

Learning is assessed as the change in speech sounds (speech formant frequencies) on a 0 to 100 scale.

Speech Perception

Time Frame: Perception is evaluated prior to and after perceptual training (30 minute session)

Auditory speech perception evaluates auditory classification and is assessed on a 0 to 100 scale. All conditions of skin stretch involve the same speech perception task.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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