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Clinical Trials/NCT02290587
NCT02290587
Completed
N/A

Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients

University Hospital, Bordeaux1 site in 1 country35 target enrollmentNovember 2015

Overview

Phase
N/A
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
University Hospital, Bordeaux
Enrollment
35
Locations
1
Primary Endpoint
Brain activation networks during MRI
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

In recent years, studies have brought knowledge of the difficulties of social cognition in Multiple Sclerosis (MS). The brain tissue alteration at the origin of these difficulties in social cognition mechanisms remain poorly understood. Although recent behavioral studies indicated social disturbances in many of these patients, functional studies investigating specific theory of mind in MS are lacking. The use of new techniques for morphological and functional Magnetic Resonance Imaging (MRI) can identify brain activation networks, mapping the achievement and tissue integrity may be related to disorders of social cognition and cognitive. The investigators propose to study social cognition in MS patients using morphological and functional imaging to determine the mechanisms underlying phenomena such as cerebral compensation and its relationship with cognitive impairment.

Registry
clinicaltrials.gov
Start Date
November 2015
End Date
March 2017
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Bordeaux
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Brain activation networks during MRI

Time Frame: At inclusion (day 0)

To identify brain activation networks during the two paradigms of theory of mind and executive function in RRMS patients taking into account cognitive impairment.

Secondary Outcomes

  • Reduction of volume of deep brain structures and reduction of cortical thickness(At inclusion (day 0))
  • White matter skeleton on Fractional Anisotropy (FA) maps established by voxel-based.(At inclusion (day 0))

Study Sites (1)

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