Transcutaneous acupoint electrical stimulation improves postoperative sleep of patients with gastrointestinal tumors by regulating the Nrf2/ARE signal pathway

Not Applicable

Recruiting

• Conditions: gastrointestinal tumor

• Registration Number: ITMCTR2100005469
• Lead Sponsor: Xuzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Patients undergoing elective laparoscopic gastrointestinal tumor surgery
2.Age: 18 to 75 years old
3.American Association of Anesthesiologists (ASA) grade I to III
4.BMI 18.5kg/m2 - 28kg/m2
5.Preoperative clinical tumor TNM staging: cTis-3N0-1M0 (refer to AJCC/UICC 8th edition TNM staging)

Exclusion Criteria

1. PSQI>7 points. 2.Sleep apnea, or moderate or more snoring. 3. Preoperative sinus bradycardia (heart rate less than 50 beats/min) or sinus node disease, second-degree or third-degree atrioventricular block, and pacemaker. 4.Long-term use of anticonvulsants, antidepressants or other psychotropic drugs. 5. Those who are highly sensitive or allergic to the drugs or equipment in this study. 6.Severe heart, liver or kidney disease. 7. Participated in other clinical trials in the past 3 months. 8.Hearing and language communication barriers, unable to communicate effectively with doctors. 9. Patients who are pregnant or breastfeeding. 10.Patients with fever or infection before surgery.11.Patients who live with critically ill patients or live in a ward with> 3 persons.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AIS score;PSQI score;

Secondary Outcome Measures

Name	Time	Method
HRV physiological data;Time of first air exhaust after operation;Liquid in and out;operation time;VAS score;Anesthesia time;Intraoperative remedies;Intraoperative blood pressure;Analgesic use;Body temperature changes;Hospital stay;Adverse events and medication;