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Comparing Optimized Models of Primary And Specialist Services for Palliative Care: Pilot Feasibility Trial

Not Applicable
Recruiting
Conditions
Seriously Ill Hospitalized Patients
Interventions
Behavioral: Standardized Usual Care
Behavioral: Default Order
Behavioral: Accountable Justification
Registration Number
NCT06629142
Lead Sponsor
University of Pennsylvania
Brief Summary

Palliative care (PC) seeks to reduce suffering and improve quality of life for patients with serious illnesses and their families. National guidelines recommend that clinicians either provide palliative care themselves (generalist PC) or consult experts (specialist PC) as a standard part of serious illness care. This feasibility pilot study will be conducted with 6 hospitals at two large U.S. health systems and enroll 540 seriously ill hospitalized patients. Eligibility is determined by a mortality prediction score where enrolled patients have at least a 60% risk of dying within 1 year. Enrollment assessment occurs as close as possible to 36 hours post admission. In this cluster-randomized trial, the 6 hospitals will be randomized to 3 arms: (1) standardized usual care, (2) trained generalist PC, or (3) specialist PC. Generalists are trained using the Center to Advance Palliative Care (CAPC) online trainings. The pilot study will only measure process outcomes to assess the feasibility of a larger clinical trial (e.g., are the interventions working as intended). This pilot feasibility study is the precursor to a much larger pragmatic, hybrid effectiveness-implementation parallel-cluster RCT that will assess the comparative effectiveness of triggering generalist PC and specialist PC on several patient-centered outcome measures.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
540
Inclusion Criteria
  • Age 18 years of age or older; AND
  • Predicted 1-year mortality risk of 60% or greater; AND
  • Admitted to a study hospital.
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Exclusion Criteria
  • Patients who die or have an active or completed discharge order prior to enrollment time
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standardized Usual CareStandardized Usual CareActive control group, where moderately high-risk patients (e.g., with a 1-year mortality risk between 60% and 94%) will receive usual care. A specialist PC consult is ordered by default for the highest-risk patients (i.e., 1-year mortality risk ≥ 95%), unless clinicians cancel the order.
Trained Generalist Palliative CareDefault OrderGeneralist clinicians trained in PC domains receive an EHR-based alert to document whether or not they have addressed PC domains for moderately high-risk patients ('accountable justification intervention'). A specialist PC consult is ordered by default for the highest-risk patients unless clinicians cancel the order.
Trained Generalist Palliative CareAccountable JustificationGeneralist clinicians trained in PC domains receive an EHR-based alert to document whether or not they have addressed PC domains for moderately high-risk patients ('accountable justification intervention'). A specialist PC consult is ordered by default for the highest-risk patients unless clinicians cancel the order.
Specialist Palliative CareDefault OrderA specialist PC consult is ordered by default for all patients with a ≥ 60% 1-year mortality risk ('default order intervention'), unless clinicians cancel the order.
Primary Outcome Measures
NameTimeMethod
Appropriate Firings of All Our Practice Advisory (OPA) Interventions36 to 60 hours post admission

Percentage of all Intervention Our Practice Advisory (OPAs) that fired in the correct time window for patients with mortality risk thresholds eligible for each intervention.

Secondary Outcome Measures
NameTimeMethod
Patient-Reported Outcome (PRO) Survey Response Rate at 1 monthEnrollment - 1 month post-discharge

Percentage of 1-month PRO surveys completed by alive patients or their surrogate proxies

PRO Survey Response Rate at 3 monthsEnrollment - 3 months post-discharge

Percentage of 3-month PRO surveys completed by alive patients or their surrogate proxies

Default Specialist PC Consults36 hours to 170 hours post admission

Percentage of default specialist PC orders that resulted in an inpatient PC consult before hospital discharge

Default Specialist PC Order Cancellation Rate36 hours to 60 hours post admission

Percentage of default specialist PC orders in which a generalist clinician indicated they did not want the order to proceed.

Inappropriate Our Practice Advisory (OPA) Firings0 to 60 hours post admission

Percentage of all patient encounters in whom at least one Our Practice Advisory (OPA) fired inappropriately. This includes an OPA firing outside the allowed time window on a patient who is eligible, the firing of the wrong OPA on a patient who is eligible (e.g., firing of the Generalist PC OPA for a patient in the Specialist PC arm), and the firing of any OPA on a patient who is ineligible (e.g., who has an inappropriate mortality risk score or active discharge order at the time enrollment eligibility is assessed).

Generalist PC Training CompletionBaseline

Percentage of clinicians eligible for CAPC palliative care training in the Generalist PC arm who complete the 4 required training modules. Partial completion (1-3 required modules) and completion of optional CAPC modules will be secondarily reported.

Generalist PC Domain Completion36 hours to 60 hours post admission

Percentage of clinicians in the Generalist PC arm who say they are addressing patients' PC needs during the current encounter, and of those, the percentage who document at least 1 of 4 PC Domains in the EHR Our Practice Advisory Alert

Trial Locations

Locations (2)

Kaiser Permanente Southern California

🇺🇸

Pasadena, California, United States

Trinity Health

🇺🇸

Livonia, Michigan, United States

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