Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1
Phase 1
Completed
- Conditions
- Cocaine-Related Disorders
- Registration Number
- NCT00265265
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Brief Summary
The purpose of this study is to assess potential interactions between intravenous (i.v.) cocaine and atomoxetine (Strattera) administered orally in four escalating doses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- 18-45 years of age who are not seeking treatment at the time of the study
- Must be able to provide written informed consent
- Must be within 20 percent of ideal body weight and weigh at least 45 kg
- Must meet DSM0IV diagnostic criteria for cocaine abuse or dependence
- Must currently be using cocaine as confirmed by a positive BE
- If female and of child bearing potential, must agree to the use of birth control
Exclusion Criteria
- please contact the site directly for more information
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Cardiovascular responses Safety
- Secondary Outcome Measures
Name Time Method Abuse Liability Mood and personality assessments Cocaine craving pharmacokinetic assessment Psychological Effects of Cocaine
Trial Locations
- Locations (1)
Uniformed Services University of Health Science
🇺🇸Bethesda, Maryland, United States