Assessment of Potential Interactions Between Cocaine and Tolcapone - 1
Phase 1
- Conditions
- Cocaine-Related Disorders
- Registration Number
- NCT00033059
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Brief Summary
The purpose of this study is to assess the potential interactions between intravenous (IV) cocaine and tolcapone.
- Detailed Description
Double-blind, inpatient study by screening responses to cocaine infusions of 20 and 40 mg i.v. subjects into 1 of 2 treatment groups to assess potential interactions between i.v. cocaine infusion and treatment with tolcapone.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Volunteers dependent on cocaine and are non-treatment seeking; between 18-45 yrs of age; DSM-4 criteria for cocaine abuse or dependence
Exclusion Criteria
Additional criteria available during screening at the site
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UCLA Integrated Substance Abuse Program
🇺🇸Los Angeles, California, United States