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Interactions Between Cocaine and Ethanol and Disulfiram - 1

Phase 1
Conditions
Alcohol-Related Disorders
Cocaine-Related Disorders
Registration Number
NCT00094289
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Brief Summary

The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

Detailed Description

This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
16
Inclusion Criteria
  • Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment.
  • Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements.
Exclusion Criteria
  • Please contact site for more information.

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Safety assessments
Psychological effects
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

University of Texas Hlth Sci Ctr San Ant

🇺🇸

San Antonio, Texas, United States

UCLA Integrated Substance Abuse Program

🇺🇸

Los Angeles, California, United States

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