COMPARISON BETWEEN LEVOBUPIVACAINE PLUS DEXMEDETOMIDINE V/S LEVOBUPIVACAINE PLUS CLONIDINE IN TAP BLOCK FOR POSTOPERATIVE ANALGESIA FOLLOWING INGUINAL HERNIA REPAIR

Not yet recruiting

• Conditions: Unilateral inguinal hernia, without obstruction or gangrene, (2) ICD-10 Condition: K409||Unilateral inguinal hernia, without obstruction or gangrene,

• Registration Number: CTRI/2021/05/033559
• Lead Sponsor: Dr Rashmi Thakur

Brief Summary

This is a interventional comparative randomized study to see the effect of dexmedetomidine and clonidine as an adjuvant to levobupivacaine in TAP block for post operative analgesia in 74 patients of age group 18 to 65 years with ASA  physical status I-II undergoing unilateral uncomplicated inguinal hernia .It will be conducted at single center in India. Primary outcome measures will be duration of analgesia with dexmedetomidine and clonidine as an adjuvant to levobupivacaine in TAP block. Secondary outcome will be quality of pain relief, total dose of rescue analgesic in24 hours and incidence of side effects.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-17
• Last Update Posted: 2021-11-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Male
• Target Recruitment: 74

Inclusion Criteria

Asa grade I & II age group 18-65 years height 140-170cm weight 30-90 kg BMI<30 kg/m2 male patients who will be undrgoing elective, uncomplicated inguinal hernia reapir under subarachnoid block.

Exclusion Criteria

• 1.Refusal to enroll 2.
• Non-cooperative patients 3.
• Pre-existing abdominal pain.
• Patients on analgesic drugs.
• Duration of surgery>2 hours 6.
• Any intraoperative surgical complications.
• Systemic disorders- liver, kidney, cardiac, respiratory, neurological, psychiatric disorders and bleeding tendencies.
• Patients with history of allergic reactions to local anesthetics.
• Presence of any contraindication to neuraxial anesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
duration of analgesia with dexmedetomidine and clonidine as an adjuvant to levobupivacaine in TAP block.	Within 24 hours

Secondary Outcome Measures

Name	Time	Method
Quality of pain relief as assessed by VAS.	Total dose of rescue analgesic in 24 hours.

Trial Locations

Locations (1)

Dr Bhimrao Ambedkar Memorial Hospital; 🇮🇳 Raipur, CHHATTISGARH, India

Dr Bhimrao Ambedkar Memorial Hospital

🇮🇳Raipur, CHHATTISGARH, India

Dr Indresh Yadav

Principal investigator

8109938709

indreshyadav91@gmail.com