Investigation of enzymatic liver funtion in Fontan-palliated patients

• Conditions: Q20.9; K74.6; Congenital malformation of cardiac chambers and connections, unspecified; Other and unspecified cirrhosis of liver

• Registration Number: DRKS00022517
• Lead Sponsor: DHZB

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-28
• Study Completion: 2022-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Fontan patients > 18 years

Exclusion Criteria

pediatric patients < 18 years
allergic reaction to paracetamol/methacetin

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is the result of the LiMAx test, which quantifies the enzymatic liver function.

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes are the changes of the liver function in dependance of the time after the Fontan operation and its correlation with sonographic parenchymal changes or serological hepatic markes.