Effect of Sensory Electrical Stimulation on Resting Tremors in Patients with Parkinson's Disease

Not Applicable

Recruiting

• Conditions: Parkinson Disease

• Registration Number: NCT06646510
• Lead Sponsor: Cairo University

Brief Summary

Parkinson's disease is one of the most prevalent motor disorders in the world . The disease is progressive and has no known treatment. In addition to a number of psychological and autonomic issues, the disease also cause movement abnormalities which are the most challenging problem because management is still limited by medication or traditional physiotherapy the most effective way to treat symptoms is through an interprofessional new modalities as sensory stimulation , this study will be the first of its type to measure the effect of sensory stimulation on static tremors. Also, this study is the first of its type to make a continues treatment protocol for patient with static tremors.

SO the purpose of these study will To investigate the effect of sensory electrical stimulation on resting tremors in Parkinson's patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-01
• Status Verified: 2024-10
• Study First Submitted: 2024-10-15
• Study First Submitted QC: 2024-10-15
• Study First Posted: 2024-10-17
• Last Update Submitted: 2024-10-17
• Last Update Posted: 2024-10-18
• Primary Completion: 2024-12-30
• Study Completion: 2025-01-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Age between 45 and 60
• Diagnosed with idiopathic Parkinson's disease with Magnetic resonance imaging of the brain
• All the patients will have mild to moderate symptoms based on (the Unified Parkinson's Disease Rating Scale UPDRS) ≥ 3
• Static tremors have been present at the hand and wrist
• Absence of other disorders that cause similar symptoms like dystonia

Exclusion Criteria

• History of hand trauma causes stiffness
• Presence of other neurological problems interferes with diagnosis as hemiplegic stroke
• Secondary parkinsonism (drug-induced or vascular ) which has very low tremor magnitude which can not be detected The patient has a severe visual problem that does not allow following the instructions.
• The patient educational level does not allow for following the instructions.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
triaxial gyrosensor (accelerator)	3 weeks	Three-dimensional angular motion will measured at the index finger of the more affected hand, by using triaxial gyrosensor (STM32L151, STMicroelectronics, ). The gyrosensor will embedded in an elastic band and attached on the dorsum of proximal phalanx
Fahn-tolosa- marin clinical rating scale	3 weeks	Fahn_tolosa_marin clinical rating scale( FTM) is avalid scale for asses hand tremor, it consist of two items related to the hand , 1_trmors 2_hand writing The score is form 0 to 4 , 0 mean no tremors , 4 means severe tremors

Trial Locations

Locations (1)

Outpatient clinics, Faculty of Physical Therapy, Cairo University; 🇪🇬 Giza, Egypt