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临床试验/CTRI/2025/10/095597
CTRI/2025/10/095597已完成不适用

Effect of periodontal inflammation on gingival crevicular and finger prick blood glucose in gingivitis and periodontitis groups: a cross sectional study

Ivaturi Naga Surya Akhila1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2025年10月19日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
24
试验地点
1
主要终点
To measure the amount of blood glucose in gingival crevicular blood (GCBG) and finger prick blood (FPBG) and evaluate the difference between them in patients with gingivitis and periodontitis.

研究概览

简要总结

A  cross-sectional observational study will be conducted .The aim is  to evaluate whether gingival crevicular blood (GCB), collected during routine periodontal probing, can serve as a reliable, minimally invasive alternative to finger-prick blood glucose (FPBG) testing. A total of 24 systemically healthy, non-diabetic patients aged above 18 years with at least 20 teeth will be recruited and divided into two groups—gingivitis and periodontitis. Blood glucose levels will be assessed from both GCB and FPBG using a glucometer, while periodontal parameters including probing pocket depth, clinical attachment level, and bleeding on probing will be recorded to calculate Periodontal Inflamed Surface Area (PISA) and Periodontal Epithelial Surface Area (PESA). The study seeks to compare and correlate GCB and FPBG values with PISA and PESA to determine the impact of periodontal inflammation on glucose levels. Findings are expected to validate the use of GCB as a convenient, non-invasive chairside tool for opportunistic diabetes screening in dental practice while highlighting the systemic implications of periodontal disease

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients who are not under any medication.

排除标准

  • Patients with abnormally low or high hematocrits, as well as those with severe cardiovascular, hepatic, immunologic, renal, hematological, or other organ disorders, patients who required antibiotic premedication or who took coagulation-interfering medications, such as heparin, non-steroidal anti-inflammatory drugs, or coumarin derivatives were excluded.patients with known diabetes.

结局指标

主要结局

To measure the amount of blood glucose in gingival crevicular blood (GCBG) and finger prick blood (FPBG) and evaluate the difference between them in patients with gingivitis and periodontitis.

时间窗: baseline

次要结局

  • To find out whether GCB can be used as a non-invasive, chairside tool to measure blood sugar levels.
  • To calculate PISA and PESA values and assess their relation with GCBG and FPBG in patients with gingivitis and periodontitis.

研究者

发起方
Ivaturi Naga Surya Akhila
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Ivaturi Naga Surya Akhila

Gsl Dental College Rajahmundry

研究点 (1)

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