Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Changes in anterior chamber after LPI at 1 month
研究概览
简要总结
The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness
详细描述
In the study ,primary angle closure(PAC) and primary angle closure glaucoma (PACG) will be recruited. Anterior segment optical coherence tomography images captured before and after laser peripheral iridotomy will be analysed to provide objective and reproducible quantification of anterior segment biometric parameters.The outcomes can provide useful information for clinical strategies in the treatment and management of pathology related to angle closure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1 .The gonioscopy or UBM examination has confirmed the diagnosis of PACS or PAC
- •Intraocular pressure within 10 to 21 mmHg ，C/D≤0.6
- •Visual field is normal or only show paracentral scotoma
- •Vision or corrected visual acuity ≥0.8
- •Refractive degree no more than 200D
- •Exclude other ocular and systemic diseases
排除标准
- •Corneal macula and other corneal diseases, ocular surface disease or corneal edema
- •Iridocyclitis
- •Ocular trauma and intraocular operation history
- •No fixationFundus lesions such as diabetic retinopathy or retinal detachment
- •No fixation
- •Ocular or systemic application of cortical steroids -
结局指标
主要结局
Changes in anterior chamber after LPI at 1 month
时间窗: 1month
次要结局
未报告次要终点
研究者
Haomin Luo
Haomin Luo M.d.
Second Xiangya Hospital of Central South University