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Clinical Trials/NCT03673046
NCT03673046
Completed
Not Applicable

Smartphone Cognitive Behavioral Therapy for Body Dysmorphic Disorder: A Randomized, Waitlist-control Trial

Massachusetts General Hospital1 site in 1 country80 target enrollmentSeptember 17, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Body Dysmorphic Disorder
Sponsor
Massachusetts General Hospital
Enrollment
80
Locations
1
Primary Endpoint
Difference in BDD Severity (BDD-YBOCS) at the End of Treatment/Waitlist Period.
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The investigators are testing the efficacy of Smartphone-delivered cognitive behavioral therapy (CBT) treatment for body dysmorphic disorder (BDD). The investigators hypothesize that participants receiving app-CBT will have greater improvement in body dysmorphic disorder symptom severity than those in the waitlist condition at treatment endpoint (week 12).

Detailed Description

The primary aim of this study is to test the efficacy of a Smartphone-based cognitive behavioral therapy (CBT) treatment for adults with body dysmorphic disorder (BDD) recruited nationally. In a prior study (Clinical Trials Identifier # NCT03221738), the investigators developed and pilot-tested the feasibility, acceptability, and preliminary efficacy of a CBT for BDD app in an open pilot trial. The investigators are now further testing these outcomes in a randomized controlled trial. Eligible subjects (N= 64) will be randomly assigned to 12-weeks of Smartphone-delivered CBT for BDD either immediately, or after a 12-week long waiting period (50/50 chance).

Registry
clinicaltrials.gov
Start Date
September 17, 2019
End Date
October 3, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sabine Wilhelm, PhD

Chief of Psychology

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • at least 18 years of age
  • current diagnosis of primary body dysmorphic disorder (BDD), based on a clinical structured diagnostic interview
  • currently living in the United States

Exclusion Criteria

  • Psychotropic medication changes within 2 months prior to enrollment (Participants taking psychotropic medication must have been on a stable dose for at least 2 months prior to enrollment and not change medication during study period)
  • Past participation in 4+ sessions of cognitive behavioral therapy (CBT) for body dysmorphic disorder (BDD)
  • Current severe substance use disorder
  • Lifetime bipolar disorder or psychosis
  • Acute, active suicidal ideation as indicated by clinical judgment and/or a score \>2 on the suicidal ideation subscale of the Columbia-Suicide Severity Rating Scale (C-SSRS).
  • Current severe comorbid major depression, as indicated by clinical judgment and/or a Quick Inventory of Depressive Symptomatology- Self Report (QIDS-SR) total score ≥ 21
  • Concurrent psychological treatment
  • Does not own a supported Smartphone with a data plan
  • Lack of technology literacy that would interfere with ability to engage with smartphone treatment

Outcomes

Primary Outcomes

Difference in BDD Severity (BDD-YBOCS) at the End of Treatment/Waitlist Period.

Time Frame: Week 0, Week 6, and Week 12

The BDD Yale-Brown Obsessive Compulsive Scale (BDD-YBOCS) is the gold-standard, semi-structured clinician-administered assessment of BDD severity. It contains 12 items ranging from 0 to 4, which are summed to generate a total score (range = 0 to 48). Higher scores indicate more severe BDD symptoms. The BDD-YBOCS

Secondary Outcomes

  • Difference in Delusionality at the End of Treatment/Waitlist Period(Week 0, Week 6, and Week 12)
  • Difference in Depression at the End of Treatment/Waitlist Period(Week 0, Week 6, and Week 12)
  • Difference in Functional Impairment at the End of Treatment/Waitlist Period(Week 0, Week 6, and Week 12)
  • Difference in Quality of Life at the End of Treatment/Waitlist Period(Week 0, Week 6, and Week 12)

Study Sites (1)

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