Comparing Acute Effects of Extra Virgin Coconut Oil and Extra Virgin Olive Oil Consumption on Appetite and Food Intake in Normal Weight and Obese Male Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- triglycerides change
研究概览
简要总结
The aim of this study is to compare acute effects of consuming extra virgin coconut oil (EVCO) as a source of medium chain fatty acids and extra virgin olive oil (EVOO) as a source of long chain fatty acids in normal weight and obese subjects.
详细描述
Twenty male subjects (10 normal weight; 10 obese) consumed breakfast meals containing skimmed milk, fat-free white cheese, bread and EVCO (25 g) or EVOO (25 g). Visual analog scale evaluations, resting metabolic rate measurements and selected blood parameters analysis (glucose, triglyceride, insulin and plasma peptide YY) were performed before and after the test breakfast meals. In addition, energy intakes were evaluated by ad libitum lunch meal at 180 min.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Metabolically healthy
- •Aged 19-40 years
- •Normal weight (BMI=18.5-24.9 kg/m²) and obese men (BMI=30-34.99 kg/m²)
排除标准
- •alcohol consumption,
- •weight gain/loss recently (> %5, in three months),
- •any genetic and metabolic diseases,
- •any food allergy/intolerance,
- •any medication,
- •restrained eating habits.
结局指标
主要结局
triglycerides change
时间窗: 0, 30, 60, 120, 180 minutes
mg/dl
Ad libitum energy intake
时间窗: 180 minute
kcal
Energy expenditure change
时间窗: 0, 60, 120, 180 minutes
kcal
Subjective appetite feelings change
时间窗: 0, 30, 60, 120, 180 minutes
visual analogue scales rating (0-10 cm)
glucose change
时间窗: 0, 30, 60, 120, 180 minutes
mg/dl
insulin change
时间窗: 0, 30, 60, 120, 180 minutes
mU/L
peptide YY change
时间窗: 0, 30, 60, 120, 180 minutes
pg/dl
次要结局
未报告次要终点
研究者
Ziyaerokaymetin
Principal Investigator
Ankara City Hospital Bilkent