Comparing EVCO and EVOO

Not Applicable

Completed

• Conditions: Appetitive Behavior; Obesity
• Interventions: Other: Extra virgin coconut oil or extra virgin olive oil

• Registration Number: NCT04738929
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

The aim of this study is to compare acute effects of consuming extra virgin coconut oil (EVCO) as a source of medium chain fatty acids and extra virgin olive oil (EVOO) as a source of long chain fatty acids in normal weight and obese subjects.

Detailed Description

Twenty male subjects (10 normal weight; 10 obese) consumed breakfast meals containing skimmed milk, fat-free white cheese, bread and EVCO (25 g) or EVOO (25 g). Visual analog scale evaluations, resting metabolic rate measurements and selected blood parameters analysis (glucose, triglyceride, insulin and plasma peptide YY) were performed before and after the test breakfast meals. In addition, energy intakes were evaluated by ad libitum lunch meal at 180 min.

Study Timeline

• Study Start: 2019-01-03
• Primary Completion: 2019-06-03
• Study Completion: 2019-06-03
• Study First Submitted: 2021-01-20
• Status Verified: 2021-02
• Study First Submitted QC: 2021-02-03
• Last Update Submitted: 2021-02-03
• Study First Posted: 2021-02-04
• Last Update Posted: 2021-02-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• Metabolically healthy
• Aged 19-40 years
• Normal weight (BMI=18.5-24.9 kg/m²) and obese men (BMI=30-34.99 kg/m²)

Exclusion Criteria

• smoking,
• alcohol consumption,
• weight gain/loss recently (> %5, in three months),
• any genetic and metabolic diseases,
• any food allergy/intolerance,
• any medication,
• restrained eating habits.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Obese	Extra virgin coconut oil or extra virgin olive oil	Obese subjects (BMI=30-34.99)
Normal weight	Extra virgin coconut oil or extra virgin olive oil	Normal weight subjects (BMI=18.5-25)

Primary Outcome Measures

Name	Time	Method
glucose change	0, 30, 60, 120, 180 minutes	mg/dl
triglycerides change	0, 30, 60, 120, 180 minutes	mg/dl
Ad libitum energy intake	180 minute	kcal
Energy expenditure change	0, 60, 120, 180 minutes	kcal
Subjective appetite feelings change	0, 30, 60, 120, 180 minutes	visual analogue scales rating (0-10 cm)
insulin change	0, 30, 60, 120, 180 minutes	mU/L
peptide YY change	0, 30, 60, 120, 180 minutes	pg/dl

Trial Locations

Locations (1)

Presidency of Republic of Turkey Health Center; 🇹🇷 Ankara, Turkey