Comparison of efficacy of two treatment of psoriais (Bath PUVA with topical steroids andMethotrexate with topical steroids)- an observational study
Not Applicable
- Conditions
- Health Condition 1: L409- Psoriasis, unspecified
- Registration Number
- CTRI/2020/02/023198
- Lead Sponsor
- Kasturba Medical College Manipal academy of Higher education Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult consenting patients of 18years of age and above, suffering from psoriasis vulgaris, who are initiated on methotrexate and topical steroids (Clobetasol propionate 0.5% cream in 30/70 concentration) or bath-PUVA with topical steroids (Clobetasolbpropionate 0.5% cream in 30/70 concentration) as part of treatment.
Exclusion Criteria
1. Patients on systemic and topical agents, (except topical steroids) which will precipitate/treat psoriasis. Wash out period of 4 half lives will be considered in case of previously treated patients.
2. Children less than 18 years of age
3. Pregnant and lactating women
4. Severe systemic comorbidities.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AIM: To compare the efficacy of bath PUVA and methotrexate in psoriasis vulgaris <br/ ><br>Timepoint: less than 1 yr <br/ ><br>
- Secondary Outcome Measures
Name Time Method OBJECTIVE: <br/ ><br>1. To assess the number of sessions needed to achieve PASI50 /PASI75/ PASI 100 with bath <br/ ><br>PUVA and number of doses of methotrexate for the same. <br/ ><br>2. To assess the time duration for relapse after the aforementioned control of the disease <br/ ><br>with bath-PUVA and methotrexate <br/ ><br>3. To assess the side effects and patient satisfaction with bath-PUVA and methotrexate.Timepoint: less than 1 yr