Comparision between two different anaesthesia techniques - one opioid based and another opioid free in patients undergoing open abdominal surgery for gynaecological (female genital tract) cancer
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Gynaecological MalignancyHealth Condition 2: C51-C58- Malignant neoplasms of female genital organs
- Registration Number
- CTRI/2018/04/013335
- Lead Sponsor
- All India Institute of Medical Sciences New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
ASA I-II scheduled to undergo Elective open gynaecological oncology surgery under general anaesthesia
Exclusion Criteria
1)Patients refusal
2)ASA III OR IV
3)Allergy to any of the study drugs
4)Contraindications to regional technique e.g., allergy to local anaesthetic drugs, infection around site of block ,any coagulation disorder, sepsis
5)History of analgesic dependence (long term use) and opiate tolerance
6)Pre-existing chronic pain with regular use of medications
7)Epilepsy and psychiatric disturbances
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to attain the PACU discharge criteriaTimepoint: post operative period 2 hours
- Secondary Outcome Measures
Name Time Method Opioid induced hyperalgesia (OIH)Timepoint: at PACU discharge and at 24 hours;Post-operative analgesic consumptionTimepoint: for 24 hours;Post-operative nausea and vomiting(PONV)Timepoint: till 24 hours;Quality of recovery as measured by QoR- 15 questionnaireTimepoint: at 12 and 24 hours;Time to extubationTimepoint: time from switching off inhalational agent to extubation;Time to first analgesic in PACUTimepoint: post operative period 2 hours;Time to shiftingTimepoint: time from switching off inhalational agent to shifting the patient out of theatre;VAS scoreTimepoint: on arrival in PAC