Based on the theory of ''spleen governs movement and transformation'' to explore the clinical observation and mechanism study of applying the method of clearing away heat and strengthening spleen to dissipate dampness in the treatment of gouty arthritis
- Conditions
- Gouty arthritis
- Registration Number
- ITMCTR2100005186
- Lead Sponsor
- The Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Comply with the above-mentioned western medicine diagnostic criteria and traditional Chinese medicine diagnostic criteria at the same time, and the syndrome belongs to the accumulation of damp-heat syndrome;
(2) Aged 18 to 70 years old with acute phase of gout, and the symptoms reach their peak within 48 hours;
(3) not taken other drugs for gouty arthritis at the same time.
(1) The blood uric acid level is lower than the upper limit of the reference range of normal values (200-415umol/L in the reference range of blood uric acid in the Laboratory Department of the Third Affiliated Hospital of Beijing University of Chinese Medicine);
(2) Patients who are allergic to NSAIDs drugs;
(3) Patients with other rheumatic immune diseases, serious primary diseases such as cardiovascular, liver, kidney, brain, digestive system and hematopoietic system, and mental illness;
(4) Those who are severely deformed and incapacitated by advanced arthritis;
(5) Pregnant and lactating women;
(6) Patients with active gastrointestinal disease, and patients with peptic ulcer within one month before this study;
(7) Patients who are currently participating in or have participated in clinical studies of other treatments within 4 weeks before this study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Erythrocyte sedimentation rate;Uric acid;Visual analogue pain score;Musculoskeletal Ultrasound;white blood cell;Serum C-reactive protein;Joint swelling and pain index;
- Secondary Outcome Measures
Name Time Method