Functional evaluation of the gastric conduits after esophagectomy using High Resolution Manometry (HRM) and 24hr-pH monitoring examinatio
- Conditions
- Esophageal Cancer
- Registration Number
- JPRN-UMIN000030733
- Lead Sponsor
- niversity of Tokyo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Not provided
1) Spent less than 1 year after the surgery (except for preoperative patients). 2) Have contraindications to Esophagogastroduodenoscopy. 3) Have contraindications to High Resolution Manometry examination, which are determined by the device distributor. 4) Have difficulties in completing 24-hour pH monitoring. 5) Have severe hoarseness and/or dysphagia and difficult to swallow with the catherters intranasally inserted. 6) Impossible to suspend drug intakes: enterokinetic agents, antiacid agents, cholinergic or anti-cholinergic agents for other diseases than esophageal cancer. 7) Proved to have residual food inside gastric conduit during esophagogastroduodenoscopy. 8) Have allergies with the drugs used in the study examination. 9) Pregnant. 10) Already participated in the study within 1 year. 11) Have other ineligible factors judged by the researchers of the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Differences in peristaltic intensity among gastric conduit reconstruction strategies in the fasting state. 2) Differences in DeMeester scores/Time percentage below pH4 at the (remnant) esophagus levels among gastric conduit reconstruction strategies.
- Secondary Outcome Measures
Name Time Method