Attentional Impairment in People With Epilepsy
- Conditions
- Epilepsy
- Registration Number
- NCT04379128
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Epilepsy is one of the most common chronic neurological conditions.It leads to cognitive impairment in 20-50% of patients with a structural form.
In comparison with seizures, these cognitive disorders are a major additional factor in occupational, social and family disability. They are particularly frequent (50%) in temporal epilepsies and preferably concern memory and language skills.
The cognitive consequences of epilepsy are therefore well described in the following areas: episodic memory, language, executive functions.
Concerning attentional abilities, a recent review has highlighted the lack of work in this specific field in order to properly measure the prevalence and nature of attentional disorders in epileptic patients. Indeed, attentional abilities are often mentioned in studies, but attention is a complex domain defined by four modalities: alertness, selective attention, divided attention and sustained attention. No study systematically assesses all of these modalities.
The objective of this study is to evaluate the prevalence and nature of attentional disorders in epileptic patients compared to control subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 272
- Patient with epilepsy, according to Fisher et al. (2005).
- Patient with written informed consent
- affiliation to a social security regime is compulsory
- Individuals who have received full information about the organization of the research and have not objected to their participation and the use of their data.
- Patient 18 years of age and older
Normal controls:
Individuals who have received full information about the organization of the research and have not objected to their participation and the use of their data.
- People 18 years of age and older
- People with no neurological and/or psychiatric history
for patients: with another progressive neurological condition for all People of full age who are subject to a legal protection measure or who are unable to express their consent People deprived of their liberty by a judicial or administrative decision People who regularly use psychoactive substances (cannabis, alcohol...)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method d2-r 10 minutes selective attention task
- Secondary Outcome Measures
Name Time Method sustained attention TAP Subtest 15 minutes Your task is to press the key as quickly as possible whenever two successive patterns have the same shape
alertness attention TAP Subtest 8 minutes a cross appears on the screen. press the key when the cross appears
divided attention TAP Subtest 5 minutes first task :a cross appears on the screen in which a varying number of crosses appear simultaneously. when four of these crosses form a square, then please press the key as quickly as possible.
second task: in this task you will hear a high and a low tone in sequence. you must decide whether the same tone occurs twice in a row. Please press the key as quickly as possible.