Study of Attentional Disorders in Patients Suffering From Idiopathic Generalized Epilepsy.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Epitrack scale score
研究概览
简要总结
Attentional disorders have been reported in neuropsychological studies evaluating patients suffering from generalized idiopathic epilepsy, but the data are disparate (in terms of test protocol). We aim to describe attentional and executive function disorder in IGE thanks to the Epitrack scale, validated in this specific population. Our secondary objective is to study the dynamic of cortical activity during an attentional task (the ANT), in order to describe the alteration of cortical networks in epileptic patients presenting with attentional disturbance.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Idiopathic generalized epilepsy followed-up during at least 2 years
- •At least one antiepileptic drug medication
- •No cognitive decline (MoCA score >26)
- •Absence of concomitant pathology that could interfere with the purpose of the study.
- •Be affiliated to the social security system
- •Have signed an informed consent
排除标准
- •Pregnancy
- •Not able to give consent (Article 1121-8 of the CSP) Vulnerable person Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP) Have a high probability of not respecting the protocol or of abandoning the study
结局指标
主要结局
Epitrack scale score
时间窗: At 1 month after inclusion
EPITrack-Score shows the performance of attention and executive functions. Higher values indicate a better performance. scale from 9-49 (9 worst score - 49 best score)
次要结局
- D2-R test score(At 1 month after inclusion)
- STAI scale(At 1 month after inclusion)
- Raven's progressive matrice scores(At 1 month after inclusion)
- Montreal Cognitive Assessment (MoCA) score(At 1 month after inclusion)
- quality of life using the Qolie-31 self questionnaire(At 1 month after inclusion)
- BDI-II score(At 1 month after inclusion)
- High resolution Electro Encephalo Gram functional connectivity markers at rest and during the ANT task(At 1 month after inclusion)