Study of Attentional Disorders in Patients Suffering From Idiopathic Generalized Epilepsy.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Idiopathic Generalized Epilepsy
- Sponsor
- University Hospital, Lille
- Enrollment
- 33
- Locations
- 1
- Primary Endpoint
- Epitrack scale score
- Status
- Terminated
- Last Updated
- 11 months ago
Overview
Brief Summary
Attentional disorders have been reported in neuropsychological studies evaluating patients suffering from generalized idiopathic epilepsy, but the data are disparate (in terms of test protocol). We aim to describe attentional and executive function disorder in IGE thanks to the Epitrack scale, validated in this specific population. Our secondary objective is to study the dynamic of cortical activity during an attentional task (the ANT), in order to describe the alteration of cortical networks in epileptic patients presenting with attentional disturbance.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Idiopathic generalized epilepsy followed-up during at least 2 years
- •At least one antiepileptic drug medication
- •No cognitive decline (MoCA score \>26)
- •Absence of concomitant pathology that could interfere with the purpose of the study.
- •Be affiliated to the social security system
- •Have signed an informed consent
Exclusion Criteria
- •Pregnancy
- •Not able to give consent (Article 1121-8 of the CSP) Vulnerable person Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP) Have a high probability of not respecting the protocol or of abandoning the study
Outcomes
Primary Outcomes
Epitrack scale score
Time Frame: At 1 month after inclusion
EPITrack-Score shows the performance of attention and executive functions. Higher values indicate a better performance. scale from 9-49 (9 worst score - 49 best score)
Secondary Outcomes
- D2-R test score(At 1 month after inclusion)
- STAI scale(At 1 month after inclusion)
- Raven's progressive matrice scores(At 1 month after inclusion)
- Montreal Cognitive Assessment (MoCA) score(At 1 month after inclusion)
- quality of life using the Qolie-31 self questionnaire(At 1 month after inclusion)
- BDI-II score(At 1 month after inclusion)
- High resolution Electro Encephalo Gram functional connectivity markers at rest and during the ANT task(At 1 month after inclusion)