Prognostic Value of Finger Blood Pressure in Arteriovenous Fistula Care

Not Applicable

Completed

• Conditions: End Stage Renal Disease; End-Stage Kidney Disease; Dialysis Access Dysfunction

• Registration Number: NCT06765577
• Lead Sponsor: Singapore General Hospital

Brief Summary

The goal of this trial is to investigate the prognostic value of monitoring finger blood pressures (FBPs) in predicting the success of surgically created arteriovenous fistula (AVF) for patients with end stage renal disease. The main questions it aims to answer is:

- Can FBPs predict AVF maturation?

Participants will undergo FBP measurements at pre-op, immediately post-op, 4 weeks and 6 weeks post-AVF creation.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-05
• Primary Completion: 2019-12-27
• Study Completion: 2020-02-10
• Status Verified: 2024-11
• Study First Submitted: 2024-11-12
• Study First Submitted QC: 2025-01-03
• Last Update Submitted: 2025-01-03
• Study First Posted: 2025-01-09
• Last Update Posted: 2025-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Participants has documented Chronic Kidney Disease (CKD), determined by Glomerular Filtration Rate (GFR)
• Participant is recommended for renal replacement therapy based on clinical assessment of renal function as well as CKD staging, as documented in clinical notes.
• Haemodialysis was chosen as the most appropriate renal replacement therapy
• Participant is able to consent to the creation of an AVF in preparation for hemodialysis.
• Participant is able to adhere to follow-up assessments of AVF maturation, if applicable.

Exclusion Criteria

• Subject had a previous AVF and is now undergoing surgery for another AVF creation
• Subject has amputation distal to AVF
• Subject is pregnant or planning to conceive
• Participants is unable to consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Correlation between AVF maturation and changes in Finger Blood Pressure measurements at baseline and immediately post-op	Within 24 hours	To determine whether if there are any pattern in changes observed in FBP pre and post-creation that can be used for correlation to AVF maturation.

Secondary Outcome Measures

Name	Time	Method
Correlation between AVF maturation and changes in Finger Blood Pressure measurements across other timepoints	Until 6 weeks post-operation	To determine whether changes in FBP across time points (pre-op, post-op, 4 weeks and 6 weeks post-op) is correlated with AVF maturation

Trial Locations

Locations (1)

Singapore General Hospital; 🇸🇬 Singapore, SG, Singapore