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Clinical Trials/NCT04365738
NCT04365738
Completed
Not Applicable

Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection: Prospective Randomized Controlled Trial

Istanbul Bilgi University1 site in 1 country270 target enrollmentMarch 11, 2020
ConditionsCOVID-19

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COVID-19
Sponsor
Istanbul Bilgi University
Enrollment
270
Locations
1
Primary Endpoint
Dyspnea
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study is to investigate the efficacy of pulmonary rehabilitation(PR) applied in the isolation processes of post-acute patients with mild and moderate symptoms who had positive COVID-19 test on dyspnea,muscle pain,chest expansion,lower limb muscle strength and dynamic balance,fatigue,anxiety and depression.

Detailed Description

This study was conducted with 270 patients who were the COVID-19 test was positive and isolated in their homes during post-acute periods.While one of the groups (n=135) was asked to remain isolated at home by providing patient education,a PR program was applied for 4 weeks in addition to the patients in the other group(n=135).PR consists of patient education, breathing, in-house mobilization and range of motion exercises.As the evaluation parameters,pre-treatment and post-treatment dyspnea levels with Borg scale,muscle pain with visual analog scale(VAS),functional capacities with sit-up test,chest expansions with tape measure,respiratory frequency,fatigue level with fatigue severity scale,and emotional status with hospital anxiety and depression(HAD) scale were evaluated.

Registry
clinicaltrials.gov
Start Date
March 11, 2020
End Date
April 26, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

TOMRIS DUYMAZ

Assoc.Prof.

Istanbul Bilgi University

Eligibility Criteria

Inclusion Criteria

  • Between the ages of 28-45, positive COVID-19 test, being in the post-acute period, having symptoms of mild-moderate severity, respiratory rate ≤40 breaths / min, patients who can make video speech

Exclusion Criteria

  • Severe symptom involvement, fever more than 38 degrees, obese patients, patients with multiple comorbidities, patients with one or more organ failure, oxygen saturation in the blood ≤95%, a resting blood pressure of \<90/60 mmHg or\> 140 / 90 mmHg patients

Outcomes

Primary Outcomes

Dyspnea

Time Frame: Baseline, up to 4 weeks

The Borg scale is a scale scored between 0-10, indicating the severity of dyspnea. 0 indicates no shortness of breath, 10 indicates severe shortness of breath

Secondary Outcomes

  • Fatigue severity(Baseline, up to 4 weeks)
  • Hospital anxiety and depression scale(Baseline, up to 4 weeks)
  • Chest expansion(Baseline, up to 4 weeks)
  • Visual Analog Scale for pain(Baseline, up to 4 weeks)

Study Sites (1)

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